{"id":4631,"date":"2025-10-18T14:52:51","date_gmt":"2025-10-18T12:52:51","guid":{"rendered":"https:\/\/pathotec.ch\/produkt\/kappa-light-chain-antibody\/"},"modified":"2025-10-18T14:52:51","modified_gmt":"2025-10-18T12:52:51","slug":"kappa-light-chain-antibody","status":"publish","type":"product","link":"https:\/\/pathotec.ch\/en\/produkt\/kappa-light-chain-antibody\/","title":{"rendered":"KAPPA LIGHT CHAIN ANTIBODY"},"excerpt":{"rendered":"<p>Kappa recognizes surface immunoglobulin on normal and neoplastic B cells. In paraffin-embedded tissue, kappa shows strong staining of kappa-positive plasma cells and cells that have absorbed exogenous immunoglobulin. In the study of B-cell neoplasms, the determination of light chain ratios remains the focus. This is sound reasoning, as most B-cell lymphomas express either the kappa light chain antibody or the lambda light chain antibody, whereas reactive proliferations show a mixture of kappa- and lambda-positive cells. If only a single light chain type is detected, a lymphoproliferative disease is very likely. Monoclonality is determined by a kappa to lambda ratio of greater than or equal to 3:1, a lambda to kappa ratio of greater than or equal to 2:1, or a monoclonal population of 75% or more of the total population.     <\/p>\n","protected":false},"featured_media":4501,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[119,416,147],"product_tag":[448,480,481,482,479],"class_list":{"0":"post-4631","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-consumables","7":"product_cat-antibody","8":"product_cat-immunohistochemistry-en","9":"product_tag-antibody","10":"product_tag-kappa","11":"product_tag-kappa-light","12":"product_tag-kappa-light-chain","13":"product_tag-kappa-light-chain-antibody","15":"first","16":"instock","17":"shipping-taxable","18":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/pathotec.ch\/en\/wp-json\/wp\/v2\/product\/4631","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pathotec.ch\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pathotec.ch\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/pathotec.ch\/en\/wp-json\/wp\/v2\/comments?post=4631"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pathotec.ch\/en\/wp-json\/wp\/v2\/media\/4501"}],"wp:attachment":[{"href":"https:\/\/pathotec.ch\/en\/wp-json\/wp\/v2\/media?parent=4631"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/pathotec.ch\/en\/wp-json\/wp\/v2\/product_brand?post=4631"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pathotec.ch\/en\/wp-json\/wp\/v2\/product_cat?post=4631"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pathotec.ch\/en\/wp-json\/wp\/v2\/product_tag?post=4631"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}